2012年2月1日水曜日

A top secret virus, a mutations of bird flu A(H5N1)

Un virus top secret
23-01-2012

http://www.elpais.com/articulo/sociedad/virus/top/secret/elpepisoc/20120123elpepisoc_4/Tes

A top secret virus , mutations of bird flu A(H5N1)

23/01/2012 Javier Sampedro

Ron laboratories Fou-chier, in Rotterdam, and Yoshihiro Kawaoka of the University of Wisconsin have discovered mutations in the H5N1 virus become a deadly pandemic agent. This is the virus that ravaged Asian poultry farms in the past decade, and is also fatal to humans in the rare occasions that jumps the species barrier. The modified virus retains its lethality, but spreading as fast as bad news. At least among ferrets, a species almost identical to ours in its response to the flu.



"We must share data to prevent a pandemic H5N1"

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In September the two laboratories sent their results to the journals Nature and Science, but no published them yet. The review has encountered an unexpected obstacle: the scientific panel that advises the U.S. Government biosecurity (NSABB) has recommended censure. Does not object to its findings are released, but only after eliminating "methodological details that would allow people to replicate the experiments that seek to do harm."
That other scientists can replicate the results is just the golden rule that governs scientific publication: the results are not reproducible science but rumor. But do not deny the censor a point of eloquence. The head of the NSABB, Paul Keim, well justified in Nature: "It's not scare people, but the worst-case scenarios in this case are simply enormous."
The NSABB is one of the side effects of the attacks of Anthrax-tainted letters in the U.S., which despite its clumsy character managed to kill five people in 2001. The panel under the Ministry of Health American but includes scientists such as himself Keim, a specialist in infectious diseases. Nor can one say that they are fried work, from its inception in 2004, the panel has reviewed just six manuscripts, including two that described the reconstruction in 2005 the Spanish flu virus that killed 40 million people in 1918. Those items came out in Nature and Science without mutilation. Where it is inferred that the new virus must be even worse.
The panel's decision is causing broncazo consideration in the scientific community. Is the censorship justified in these cases? What should the U.S. decide? Do you still when the victims are Asian virus, the authors of the Dutch and Nature, British?
Knowing which mutations make the virus transmissible between humans is information too valuable to keep in the drawer of a barracks. It is a fact that epidemiologists in the world, with Hong Kong at the head, waited for 15 years, because they will know what they have to look at the controls poultry virus variants which run along an evolutionary disadvantage and when to recommend to their Governments drastic measures, such as farms or cremation health alerts. Data should be provided to certain scientists, and even the NSABB and admits in his report. But what scientists say. Someone will have to say. Who? Is the White House? Does WHO? By what criteria? And what scientists and from what countries? How to avoid leaks or black market gene sequences? Interestingly, the chief of infectious diseases at the University of Hong Kong, Kwok-Yung Yuen, perhaps the world most interested in the H5N1-censored data supports the recommendation of the NSABB. Remember in Nature that, in Sino-Japanese war of the thirties, Japanese military scientists infected Manchurian civilians and prisoners with plague bacteria.
Bad things have to be if we have already started with the kicks in the shins.
(Blogs.elpais.com / symmetry).


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