アジアでのSARS感染死亡に関連付けられた新種のウイルス、新型コロナウイルスが検出
UNA NUEVA ENFERMEDAD
Un virus "nunca visto en humanos" es el causante de la neumonía asiática
La confirmación del patógeno, un coronavirus, abre las puertas a la búsqueda de tratamiento
Rafael Méndez Madrid 17 ABR 2003
A NEW DISEASE
A virus "never seen in humans" is the cause of SARS
The confirmation of the pathogen, a coronavirus, opens the door to seeking treatment
Rafael Mendez Madrid 17 ABR 2003
The cause of SARS has already face. The World Health Organization (WHO) announced yesterday that pneumonia is caused "by a pathogen never before seen in humans," and that is, as suspected, "a virus from the coronavirus family." The ad, which means the beginning of the search for a treatment, was made possible by a Dutch team coronavirus inoculated a group of monkeys and these sick, something that until now had not achieved any of the 13 laboratories that has coordinated the WHO to identify and find treatment.
moreWHO is optimistic about the test of a German companyHealth ruled that the patient suffers the disease AlicanteHong Kong and Singapore take travelers temperatureWHO inspectors uncovered 200 cases of pneumonia in Beijing hiddenThe confirmation of a case of atypical pneumonia in India rises to 26 affected countries
The discovery occurred just five weeks after alerted WHO on SARS, and is a step forward in the fight against the disease. David Heymann, executive director of the WHO Communicable Diseases, said: "We leave behind methods such as quarantine and isolation and we must move decisively to other strategies, such as seeking specific treatment and a possible vaccine." The formal announcement was made possible by the virology laboratory of the Erasmus Centre Rotterdam (Netherlands) managed to infect a group of monkeys with the virus.
"This is the final step of Koch's postulates to identify an agent is the cause of the disease," explains Luis Enjuanes, a virologist at the National Center of Biotechnology, CSIC. "The first thing is to isolate the agent, then must be related epidemiologically to the disease, and ultimately inoculate a subject, check it contracts it, take a sample and isolate it," he adds. The Dutch researchers not inoculated in humans because there is still no treatment.
The Dutch team manager, Albert Osterhaus, said: "The first part of the fight against the virus is over." Osterhaus ensuing explained laboratory method. A group of monkeys inoculated with coronavirus, to another one metapneumovirus (WHO had stated on several occasions that a virus of this family could be present in the infection) and a third group received both. "Only monkeys that had the coronavirus [with or without the other agent] developed symptoms like those of SARS," said Osterhaus.
Coronaviruses are so called because they have a crown of protein in your deck that allows easy identification. Some viruses of this family contribute to the common cold. Experts believe that the origin of the epidemic animal. Researchers from the University of Hong Kong who isolated the virus on March 27 indicated that the genetic map confirms animal virus. Masato Tashiro, Institute of Infectious Diseases of Japan, said that "it is likely that the virus has existed for a long time in nature".
WHO has coordinated the activities of 13 laboratories from 10 countries, and is very happy with the cooperation and exchange of information. Yesterday began a two-day meeting of the heads of all laboratories to see what steps to take now. Among the centers no Spanish laboratory directly involved.
According to WHO, a priority will be seeking treatment. The U.S. government has already begun to meet with biotechnology companies to assist in the search for drugs and a vaccine against the disease, according to The New York Times. The Infectious Disease Laboratory USA has begun testing the antiviral 2,000 virus exist. Enjuanes says that "it is possible that one of them has some activity. Currently using the antiviral Ribavirin, but not working."
The vaccine for the disease after treatment will take longer. "We can now think of a vaccine, if ultimately necessary," said Klaus Stöhr, WHO researcher. The director of vaccinations in the USA, Bruce Gellin, said: "If we want a vaccine, we need the cooperation of private companies." However, firms are not so clear. "We can not get into an investigation of five or ten years for something that may be an epidemic of limited scope," said Leighton Read, the founder of Aviron vaccine.
WHO has appointed pathogens like virus Severe Acute Respiratory Syndrome (in English, SARS) and the discovery dedicated to Italian doctor Carlo Urbani. Urbani was the first physician to detect the disease in Hanoi (Vietnam), and alerted the WHO. Urbani died of pneumonia on March 29.
投稿
0 件のコメント:
コメントを投稿